Key Research Areas
- Neuropharmacology of Nausea and Emesis
- Brain-Gut Axis Signaling Mechanisms
- Translational Preclinical Models
- Chemotherapy-Induced Symptom Mechanisms
- Cardiovascular and Metabolic Pharmacology
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Core Areas of Expertise
Dr. Chan's expertise centres on experimental pharmacology and translational biomedical science, with a strong emphasis on Brain-Gut Axis signaling, physiological mechanisms underlying nausea and emesis, metabolic disorders, and cardiovascular regulation. Her work integrates advanced animal disease models, behavioural analysis, and molecular pharmacology to facilitate novel therapeutic development.
Recent Publications
2026
- Motion sickness: Multiple linear regression identifies behaviours linked to motion-induced emesis in Suncus murinus (house musk shrew)
2025
- A deep learning-based system for automatic detection of emesis with high accuracy in Suncus murinus
2024
- The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism
- Action of cocaine- and amphetamine-regulated transcript (CART) peptide to attenuate cisplatin-induced emesis in Suncus murinus (house musk shrew)
- Exploring the role of ghrelin and des-acyl ghrelin in chemotherapy-induced nausea and vomiting
2023
- Regional differences of tachykinin effects on smooth muscle and pacemaker potentials of the stomach, duodenum, ileum and colon of an emetic model, the house musk shrews
- Beneficial Effects of Bilberry (Vaccinium myrtillus) in Diabetes and Cardiovascular Disease
- Lingzhi (Ganoderma lucidum) and Cardiovascular Disease
2022
- Lack of effects of renin-angiotensin-aldosterone system activity and beta-adrenoceptor pathway polymorphisms on the response to bisoprolol in hypertension
- The actions of centrally administered nesfatin-1 on emesis, feeding, and locomotor activity in Suncus murinus (House Musk Shrew)
Awards & Patents
- Travel Grant Awards, the 81st Annual Scientific Meeting of the Japanese Circulation Society, Kanazawa, Japan, 2017.
- Travel Grant for Outstanding Abstract Awards, 2017 International Congress of Diabetes and Metabolism. Seoul, Korea, 2017.
- Travel Grant Awards, the Digestive Disease Mechanism Summit at UEG Week 2025, Berlin, Germany, 2025.
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