張永成博士

背景簡介

I graduated with a B.Sc. degree from The Chinese University of Hong Kong, where I received intensive training in Human Anatomy and Physiology, and I began to develop my research in the nervous system and the retina of vertebrates. After completing my undergraduate degree, I decided to further my postgraduate study at the same university and I shifted the focus of my research into developing novel drugs for cardiovascular and neurological diseases from natural products and Chinese herbal medicines. Through years of endeavors in finding and testing drugs, my study finally led me to a Ph.D. degree. Before joining the institute in 2016, I served and continued my research works in the University of Verona and later in The Chinese University of Hong Kong.

教學

統籌學科:

• Human Anatomy and Physiology
• Human Pathophysiology
• Life Sciences
• Clinical Microbiology

研究

研究計劃:

• 草藥提取物及當中化合物對於心血管和腦神經疾病的療效
• 中西藥相互作用
• 藥效及藥物安全測試
• 氯胺酮的藥物成癮機制

代表性著述

1. Cheung, D. W. S., Koon, C. M., Wong, P. H., Yau, K. C., Wat, E., Hung, A. S. M., Wang, Y. P., Lau, K. M., Ko, C. H., Chan, J. Y. W., Waye, M. M. Y., & Fung, K. P. (2017). Evaluating Efficacy and Safety of Combination Medication of Atorvastatin and a Herbal Formula Containing Salvia miltiorrhiza and Pueraria lobata on Hyperlipidemia. Phytotherapy Research.
2. Ko, C. H., Chau, L., Cheung, D. W. S., Koon, J. C. M., Fung, K. P., Leung, P. C., Poon, S. K., & Lau, C. B. S. (2014). An Innovative and Comprehensive Approach in Studying the Complex Synergistic Interactions Among Herbs in Chinese Herbal Formulae. In J. Poon & S. K. Poon (Eds.), Data Analytics for Traditional Chinese Medicine Research.
3. Liang, W., Cheung, D. W. S., Tang, H. C., Lam, W. P., Zhang, L., Leung, P. C., & Yew, D. T. W. (2014). Effect of 3-n-Butylphthalide from Celery on Vascular Dementia. In M. Colin & P. Victor (Eds.), Diet and Nutrition in Dementia and Cognitive Decline (pp. 963–972). Elsevier.
4. Cheung, D. W. S., Koon, C. M., Wat, E., Ko, C. H., Chan, J. Y. W., Yew, D. T. W., Leung, P. C., Chan, W. Y., Lau, C. B. S., & Fung, K. P. (2013). A herbal formula containing roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibits inflammatory mediators in LPS-stimulated RAW 264.7 macrophages through inhibition of nuclear factor κb (NFκB) pathway. Journal of Ethnopharmacology, 145(3), 776–783.
5. Cheung, D. W. S., Koon, C. M., Ng, C. F., Leung, P. C., Fung, K. P., Poon, S. K. S., & Lau, C. B. S. (2012). The roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibit atherogenic events: A study of the combination effects of the 2-herb formula. Journal of Ethnopharmacology, 143(3), 859–866.